One product.
One daily habit.
LYVA Flex. A daily gut-joint formula for people who refuse to slow down. Built on the science your GP probably hasn't mentioned yet.
Discover Flex →
LYVA Flex
A daily formula targeting the gut-joint axis. The mechanism is this: your gut microbiome drives systemic inflammation. That inflammation reaches your joints. LYVA Flex addresses both ends of that chain — gut barrier integrity and joint-focused anti-inflammatory support — in a single daily sachet.
Formulated without glucosamine. Built on peer-reviewed science published in Molecular Medicine Reports, Nature Communications, and Stem Cell Research & Therapy.
Every ingredient earns its place.
We source the clinical-grade forms used in published trials — not the cheap generic equivalent. The difference is whether the product actually works.
Prebiotic Blend
Inulin and FOS fermented by gut bacteria to produce short-chain fatty acids. SCFAs are now confirmed to protect cartilage and subchondral bone via the gut-joint axis (Han et al., Stem Cell Research & Therapy, 2025).
L-Glutamine
Primary fuel for intestinal lining cells. Supports gut barrier integrity and reduces intestinal permeability — closing the leak that allows inflammatory triggers into the bloodstream.
Berberine HCl
Modulates gut microbiome composition and directly inhibits NF-κB — the inflammatory signalling pathway that drives cartilage breakdown when gut dysbiosis is present.
Boswellia Serrata
Standardised to AKBA — the active compound that inhibits 5-LOX, blocking leukotriene synthesis. A 2026 network meta-analysis of 20 RCTs confirmed modified Boswellia formulations outperform all other joint supplements tested.
Curcumin BCM-95
7× absorption versus standard curcumin. The enhanced-bioavailability form used in the clinical trials that matter. 1000mg daily — the therapeutic dose. A 2025 meta-analysis of 21 RCTs (1,705 patients) confirmed significant CRP reduction versus placebo.
Quercetin
500mg — the dose shown in a randomised trial to produce significant improvement in pain and physical function. Inhibits matrix metalloproteinases that degrade cartilage. Synergistic with curcumin.
Full formulation available on request to registered practitioners and wholesale partners only.
Why we don't include glucosamine.
Glucosamine is in almost every joint supplement on the market. We reviewed the evidence and made a different choice. Research published in Nature Metabolism found regular glucosamine use was associated with a significantly higher likelihood of mild cognitive impairment progressing to dementia.
We're not in the business of including an ingredient in a daily supplement when serious questions exist about what it does to the rest of your body. The gut-joint axis gives us a better mechanism. We used it.
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